Evaluation Method of Hepatoprotective Effect of Health Food

Evaluation Method of Hepatoprotective Effect of Health Food

Male SD rats or male BALB/c mice

1.  CCl4-induced liver damage model

2.  APAP-induced liver damage model

3.  TAA-induced liver fibrosis model

4.  Alcohol-induced fatty liver disease model

5.  High fat diet-induced nonalcoholic fatty liver disease model

Test items are different depending on the animal model:

1.  Plasma or serum: AST, ALT, TG, TC, etc

2.  Liver: glutathione, glutathione peroxidase, superoxide dismutase, catalase, TG, TC, glutathione reductase, glutathione S-transferase, collagen, liver fibrosis markers, etc

3.  Pathological examination