Toxicity tests

Reproductive and Developmental Toxicity Studies
  • Guideline

    OECD 414、416

    TFDA 藥品非臨床試驗安全性規範

  • Test system

    The preferred rodent species is the rat and the preferred non-rodent species is the rabbit. Justification should be provided if another species is used.

  • Test Aims

    The test of reproduction to provide general information concerning the effects of a test substance on male and female reproductive performance in different period.

Skin Irritation Study in White Rabbits
  • Guideline

    OECD 404: Acute Dermal Irritation/Corrosion

  • Test system

    Rabbits

  • Test Aims

    Corrosion/irritation likely to arise from exposure to liquid or solid test substance by dermal application.

Skin Sensitization Study in Guinea Pigs (Maximization Test)
  • Guideline

    OECD406 Skin Sensitisation

    TFDA 藥品非臨床試驗安全性規範

  • Test system

    Guinea pig

  • Test Aims

    Confirm whether the substance will cause exert skin sensitization in guinea pigs.